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Comparative Effectiveness Research

Comparative effectiveness research (CER) is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat and monitor health conditions. The goal of CER is to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, and other decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. CER uses a wide range of research methods, including randomized controlled trials, observational studies, and systematic reviews, a structured assessment of evidence available from multiple primary studies.

Communicating Research

As CER results become available, there will be broader discussions about the findings and what those findings might mean for patients and other health care decision makers. Part of those discussions will focus on questions such as who can discuss and share these CER findings publicly, and on how the findings will be communicated....more

Generating & Interpreting Research

Stakeholders agree that good research has the potential to inform better health care decisions. But how do we define "good research?" Although randomized controlled trials have long been considered the gold standard of scientific studies, many researchers agree observational studies play a central role in answering certain types of questions, particularly regarding real-world behavior....more

Health Technology Assessment

Health Technology Assessment is "the systematic evaluation of properties, effects, and/or impacts of health care technology. It may address the direct, intended consequences of technologies as well as their indirect, unintended consequences. Its main purpose is to inform technology-related policymaking in health care. HTA is conducted by interdisciplinary groups using explicit analytical frameworks drawing from a variety of methods."...more

PCORI & CER Agencies

Given the billions of dollars in funding for comparative effectiveness research in the United States, it is helpful for health care decision-makers to understand which organizations are taking a primary role in the conduct of this research....more
Newsletter Volume

E.V.I.dently January 2015

NPC MessageHealth Care Outlook for 2015In this month’s Message from NPC, President Dan Leonard considers how the Affordable Care Act and stakeholders...
Blog Post

CER Tweets of the Week: New UMB Center of Excellence In CER, UIC College of Pharmacy Master’s in CER, PCORI in Lancet (January 19-23)

Comparative effectiveness research (CER) stakeholders tweeted about new educational opportunities regarding CER. They shared an announcement about a...
Blog Post

CER Tweets of the Week: The Challenges of Gray-Zone Medicine, PCORI in the Congress Blog (January 12-16)

This week, comparative effectiveness research (CER) stakeholders tweeted multiple articles regarding CER and various challenges they face. They...
Blog Post

CER Tweets of the Week: AcademyHealth Compares International CER, Resource Library on CER (January 5-9)

This week, comparative effectiveness research (CER) stakeholders tweeted about @AcademyHealth’s new paper comparing international efforts to boost...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

Washington, DC (July 29, 2014)—New research led by the National Pharmaceutical Council (NPC) can assist health care stakeholders to understand when...
Press Release

NPC Annual Stakeholder Survey: Comparative Effectiveness Research Is Important, But Impact on Health Care Decision-Making Is Still on the Horizon

(Washington, DC, May 19, 2014)—A new survey of health care stakeholders reveals continued optimism for the use of comparative effectiveness research...
Press Release

CER Collaborative Improving Health Outcomes Through New Comparative Evidence Tools

(Washington, DC, March 24, 2014)—Three peer-reviewed articles published in Value in Health offer important guidance to aid formulary decision-makers...
Press Release

NPC, UMD Study: Factors That Cause Different Treatment Responses Are Not Well Understood or Studied

Washington, DC, November 4, 2013—Although researchers and health care providers widely recognize that individuals with stage IV prostate cancer react...
Commentary and Testimony Page

NPC Comments on PCORI Proposal for Peer Review of Primary Research and Public Release of Research Findings

November 7, 2014Dr. Joe SelbyExecutive DirectorPatient-Centered Outcomes Research Institute1828 L St., NW, Suite 900Washington, DC 20036Dear Dr....
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

This month, NPC released its third annual survey on stakeholders’ views on comparative effectiveness research (CER), “The State of Comparative...
Commentary and Testimony Page

Keeping Our Eye on the CER Ball

Until the cherry blossoms begin to bloom later next month, most of the water cooler conversations in Washington will focus on the federal budget....
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
YouTube Videos

CER and the Environment for Health Care Decision-Making

The National Pharmaceutical Council’s (NPC) fourth annual survey of health care stakeholders is continuing to shed light on the current environment...
YouTube Videos

Webinar: CER Collaborative: Tools You Can Use

Collaborative members hosted a webinar explaining how to use the tools they developed to create greater uniformity and transparency when evaluating...
YouTube Videos

Patient Input on What Makes Comparative Effectiveness Research Useful

Myrl Weinberg, chief executive officer of the National Health Council, says that many patients are still concerned about how comparative...
Blog Post

CER Tweets of the Week: New UMB Center of Excellence In CER, UIC College of Pharmacy Master’s in CER, PCORI in Lancet (January 19-23)

Comparative effectiveness research (CER) stakeholders tweeted about new educational opportunities regarding CER. They shared an announcement about a...
Blog Post

CER Tweets of the Week: The Challenges of Gray-Zone Medicine, PCORI in the Congress Blog (January 12-16)

This week, comparative effectiveness research (CER) stakeholders tweeted multiple articles regarding CER and various challenges they face. They...
Blog Post

CER Tweets of the Week: AcademyHealth Compares International CER, Resource Library on CER (January 5-9)

This week, comparative effectiveness research (CER) stakeholders tweeted about @AcademyHealth’s new paper comparing international efforts to boost...
Blog Post

CER Tweets of the Week: Clinical Uncertainty in Surgery and EBM & Patient-Centered Medicine and EBM (December 29 – January 2)

This week, articles about evidence-based medicine (EBM) attracted the attention of comparative effectiveness research (CER) stakeholders on Twitter....

Research

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Commentary & Testimony