Comparative Effectiveness Research

Comparative effectiveness research (CER) is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat and monitor health conditions. The goal of CER is to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, and other decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. CER uses a wide range of research methods, including randomized controlled trials, observational studies, and systematic reviews, a structured assessment of evidence available from multiple primary studies.

Communicating Research

As CER results become available, there will be broader discussions about the findings and what those findings might mean for patients and other health care decision makers. Part of those discussions will focus on questions such as who can discuss and share these CER findings publicly, and on how the findings will be communicated....more

Generating & Interpreting Research

Stakeholders agree that good research has the potential to inform better health care decisions. But how do we define "good research?" Although randomized controlled trials have long been considered the gold standard of scientific studies, many researchers agree observational studies play a central role in answering certain types of questions, particularly regarding real-world behavior....more

Health Technology Assessment

Health Technology Assessment is "the systematic evaluation of properties, effects, and/or impacts of health care technology. It may address the direct, intended consequences of technologies as well as their indirect, unintended consequences. Its main purpose is to inform technology-related policymaking in health care. HTA is conducted by interdisciplinary groups using explicit analytical frameworks drawing from a variety of methods."...more

PCORI & CER Agencies

Given the billions of dollars in funding for comparative effectiveness research in the United States, it is helpful for health care decision-makers to understand which organizations are taking a primary role in the conduct of this research....more
Press Release

NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making

(Washington, DC, March 26, 2015)—A new survey of health care stakeholders reveals continued optimism that comparative effectiveness research (CER)...
Blog Post

#TBT: 5 Years Later—Comparative Effectiveness Research Survey & the ACA

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

CER Tweets of the Week: Upcoming Webinar on CER & the Environment for Health Care Decision-Making; PCORI Workshop on MS (March 16-20)

This week, comparative effectiveness research (CER) stakeholders shared invitations to register for the National Pharmaceutical Council’s (@npcnow)...
Blog Post

CER Tweets of the Week: Comments on GAO’s PCORI Assessment, AHRQ Shared Decision-Making Webinar, BMJ on Negative Findings (March 9-13)

This week, comparative effectiveness research (CER) stakeholders tweeted comments in response to the U.S. Government Accountability Office’s (@USGAO...
Press Release

NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making

(Washington, DC, March 26, 2015)—A new survey of health care stakeholders reveals continued optimism that comparative effectiveness research (CER)...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

Washington, DC (July 29, 2014)—New research led by the National Pharmaceutical Council (NPC) can assist health care stakeholders to understand when...
Press Release

NPC Annual Stakeholder Survey: Comparative Effectiveness Research Is Important, But Impact on Health Care Decision-Making Is Still on the Horizon

(Washington, DC, May 19, 2014)—A new survey of health care stakeholders reveals continued optimism for the use of comparative effectiveness research...
Press Release

CER Collaborative Improving Health Outcomes Through New Comparative Evidence Tools

(Washington, DC, March 24, 2014)—Three peer-reviewed articles published in Value in Health offer important guidance to aid formulary decision-makers...
Commentary and Testimony Page

NPC Comments on PCORI Proposal for Peer Review of Primary Research and Public Release of Research Findings

November 7, 2014Dr. Joe SelbyExecutive DirectorPatient-Centered Outcomes Research Institute1828 L St., NW, Suite 900Washington, DC 20036Dear Dr....
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

This month, NPC released its third annual survey on stakeholders’ views on comparative effectiveness research (CER), “The State of Comparative...
Commentary and Testimony Page

Keeping Our Eye on the CER Ball

Until the cherry blossoms begin to bloom later next month, most of the water cooler conversations in Washington will focus on the federal budget....
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
YouTube Videos

CER and the Environment for Health Care Decision-Making

The National Pharmaceutical Council’s (NPC) fourth annual survey of health care stakeholders is continuing to shed light on the current environment...
YouTube Videos

Webinar: CER Collaborative: Tools You Can Use

Collaborative members hosted a webinar explaining how to use the tools they developed to create greater uniformity and transparency when evaluating...
YouTube Videos

Engaging Patients in the Research Process

Dr. Dan Mullins, professor of pharmaceutical health services research at the University of Maryland School of Pharmacy, explains why it is important...
Blog Post

#TBT: 5 Years Later—Comparative Effectiveness Research Survey & the ACA

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

CER Tweets of the Week: Upcoming Webinar on CER & the Environment for Health Care Decision-Making; PCORI Workshop on MS (March 16-20)

This week, comparative effectiveness research (CER) stakeholders shared invitations to register for the National Pharmaceutical Council’s (@npcnow)...
Blog Post

CER Tweets of the Week: Comments on GAO’s PCORI Assessment, AHRQ Shared Decision-Making Webinar, BMJ on Negative Findings (March 9-13)

This week, comparative effectiveness research (CER) stakeholders tweeted comments in response to the U.S. Government Accountability Office’s (@USGAO...
Blog Post

CER Tweets of the Week: JCER on Relative Effectiveness Evidence; PCORI’s PCSI; GAO on AHRQ (March 2-6)

This week, comparative effectiveness research (CER) stakeholders tweeted about a series of articles published in the Journal of Comparative...
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