Comparative Effectiveness Research

Comparative effectiveness research (CER) is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat and monitor health conditions. The goal of CER is to improve health outcomes by developing and disseminating evidence-based information to patients, clinicians, and other decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. CER uses a wide range of research methods, including randomized controlled trials, observational studies, and systematic reviews, a structured assessment of evidence available from multiple primary studies.

Communicating Research

As CER results become available, there will be broader discussions about the findings and what those findings might mean for patients and other health care decision makers. Part of those discussions will focus on questions such as who can discuss and share these CER findings publicly, and on how the findings will be communicated....more

Generating & Interpreting Research

Stakeholders agree that good research has the potential to inform better health care decisions. But how do we define "good research?" Although randomized controlled trials have long been considered the gold standard of scientific studies, many researchers agree observational studies play a central role in answering certain types of questions, particularly regarding real-world behavior....more

Health Technology Assessment

Health Technology Assessment is "the systematic evaluation of properties, effects, and/or impacts of health care technology. It may address the direct, intended consequences of technologies as well as their indirect, unintended consequences. Its main purpose is to inform technology-related policymaking in health care. HTA is conducted by interdisciplinary groups using explicit analytical frameworks drawing from a variety of methods."...more

PCORI & CER Agencies

Given the billions of dollars in funding for comparative effectiveness research in the United States, it is helpful for health care decision-makers to understand which organizations are taking a primary role in the conduct of this research....more
Newsletter Volume

E.V.I.dently May 2015

MessageStepping Back to Look at ValueNPC President Dan Leonard explains that, like beauty, the value of health care is in the eye of the beholder....
Blog Post

CER Tweets of the Week (May 18-22): CER Stakeholders Tweet Discussions From #ISPORPhila; Generalizing RCT Results to Wider Populations

This week, many comparative effectiveness research (CER) stakeholders attended the International Society for Pharmacoeconomics and Outcomes Research...
Blog Post

CER Tweets of the Week: Remembering David Sackett, PCORI’s Selby at American Pain Society Annual Scientific Meeting (May 11-15)

This week, many stakeholders in the comparative effectiveness research (CER) community paused to remember the work of the late Dr. David Sackett, who...
Blog Post

CER Collaborative Continuing Education Program: Same Content. Same Instructors. Two Formats. Your Choice!

The Comparative Effectiveness Research (CER) Collaborative is now offering more flexibility to participate in its 19-hour continuing education...
Press Release

State Medicaid Directors Share Views on Comparative Effectiveness Research And Its Impact on Policy in National Pharmaceutical Council Survey

(Washington, DC, April 16, 2015)—A new survey conducted on behalf of the National Pharmaceutical Council (NPC) shows that state Medicaid directors...
Press Release

NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making

(Washington, DC, March 26, 2015)—A new survey of health care stakeholders reveals continued optimism that comparative effectiveness research (CER)...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

Washington, DC (July 29, 2014)—New research led by the National Pharmaceutical Council (NPC) can assist health care stakeholders to understand when...
Press Release

NPC Annual Stakeholder Survey: Comparative Effectiveness Research Is Important, But Impact on Health Care Decision-Making Is Still on the Horizon

(Washington, DC, May 19, 2014)—A new survey of health care stakeholders reveals continued optimism for the use of comparative effectiveness research...
Commentary and Testimony Page

NPC Comments on PCORI Proposal for Peer Review of Primary Research and Public Release of Research Findings

November 7, 2014Dr. Joe SelbyExecutive DirectorPatient-Centered Outcomes Research Institute1828 L St., NW, Suite 900Washington, DC 20036Dear Dr....
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

This month, NPC released its third annual survey on stakeholders’ views on comparative effectiveness research (CER), “The State of Comparative...
Commentary and Testimony Page

Keeping Our Eye on the CER Ball

Until the cherry blossoms begin to bloom later next month, most of the water cooler conversations in Washington will focus on the federal budget....
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
YouTube Videos

Comparative Effectiveness Research and the Environment for Health Care Decision-Making

During a March 26, 2015 webinar, the National Pharmaceutical Council discussed the results of its annual stakeholder survey on comparative...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
YouTube Videos

CER and the Environment for Health Care Decision-Making

The National Pharmaceutical Council’s (NPC) fourth annual survey of health care stakeholders is continuing to shed light on the current environment...
YouTube Videos

Webinar: CER Collaborative: Tools You Can Use

Collaborative members hosted a webinar explaining how to use the tools they developed to create greater uniformity and transparency when evaluating...
Blog Post

CER Tweets of the Week (May 18-22): CER Stakeholders Tweet Discussions From #ISPORPhila; Generalizing RCT Results to Wider Populations

This week, many comparative effectiveness research (CER) stakeholders attended the International Society for Pharmacoeconomics and Outcomes Research...
Blog Post

CER Tweets of the Week: Remembering David Sackett, PCORI’s Selby at American Pain Society Annual Scientific Meeting (May 11-15)

This week, many stakeholders in the comparative effectiveness research (CER) community paused to remember the work of the late Dr. David Sackett, who...
Blog Post

CER Collaborative Continuing Education Program: Same Content. Same Instructors. Two Formats. Your Choice!

The Comparative Effectiveness Research (CER) Collaborative is now offering more flexibility to participate in its 19-hour continuing education...
Blog Post

CER Tweets of the Week: PCORI Announces First Annual Meeting, U.S. News on PCORnet (May 4-8)

This week, comparative effectiveness research (CER) stakeholders tweeted about the theme for the Patient-Centered Outcomes Research Institute’s (@...
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