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NPC Updates - June, 2002

This Issue:

  • A Focus on Incremental Pharmaceutical Innovation

NPC IS PLEASED TO OFFER THE FOLLOWING RESOURCES RELATING TO THE CURRENT DISCUSSIONS ON THE VALUE OF INCREMENTAL PHARMACEUTICAL INNOVATIONS

  • Assessing the Impact of Pharmaceutical Innovation: A Comprehensive Framework, by Jack A. Meyer, Ph.D., 2002
    This report shows that new drugs are yielding a wide range of benefits to our society that more than justify the investment needed to produce them. This report develops a comprehensive framework for assessing the value of pharmaceutical innovation that encompasses both the cost of bringing new products to market and the direct and indirect benefits. (For more information view our Fact sheet
  • Executive Summary: Too Many Drugs? The Clinical and Economic Value of Incremental Innovations, by Albert Wertheimer, Ph.D., MBA, et al., 2002
    This summary addresses the need for a fully developed class of drugs in order to allow precision prescribing for the best health outcomes, as presented in the full report described below.
  • Too Many Drugs? The Clinical and Economic Value of Incremental Innovations, by Albert Wertheimer, Ph.D., MBA, et al., reprinted from "Research In Human Capital And Development, Investing in Health: The Social and Economic Benefits of Health Care Innovation," Vol. 14, 2001
    The history of clinical pharmacology is characterized by incremental improvements in the safety, efficacy, selectivity, and utility of drugs within a given class. This report makes the case for a fully developed class of drugs to allow precision prescribing in order to achieve optimum outcomes in the most cost effective manner.
  • The Value of Incremental Pharmaceutical Innovation for Older Americans, by Albert Wertheimer, Ph.D., MBA, et al., 2001
    This monograph explains that small incremental improvements within drug classes provide important health benefits, especially for elderly patients. The monograph illustrates that therapeutic advantages of these newer drugs in a class include: fewer side effects, improved safety and greater effectiveness; easier use, which facilitates compliance with prescribed regimens; and better tailoring to fit individual patient needs.
  • Fact sheets available at the following links:
  • Measuring the Value of Health Innovation: The Policy Implications of New Medical Technologies, A Briefing on the Benefits and Costs of Medical Progress, September 7, 2001. Featured articles, research summaries and video highlights from the symposium are available on the CD-ROM "The Value of Medical Innovation."
  • The September/October 2001 issue of the journal "Health Affairs" featured a new body of peer-reviewed research discussing the value of innovation. Taken together, this research is seminal in the national conversation on the issue of drug costs and spending. The Alliance for Health Reform, in cooperation with NPC and the Merck Foundation, sponsored a symposium and panel discussion on September 7, 2001, which focused on this new research. A transcript of the symposium is available here.

To order any of these publications in hard copy (free of charge), please go to our order form or call (703) 620-6390.

Since 1953, NPC has sponsored and conducted scientific, evidence-based analyses of the appropriate use of pharmaceuticals and the clinical and economic value of pharmaceutical innovation. NPC provides educational resources to a variety of health care stakeholders, including patients, clinicians, payers and policy makers. More than 20 research-based pharmaceutical companies are members of the NPC.

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