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Blue Pill or Red Pill: The Limits of Comparative Effectiveness Research

Comparative effectiveness research (CER) has been heralded as a way to reduce health-care costs by determining which treatments provide the most benefit for the largest number of patients. This report warns that by choosing "winners and losers," CER drug trials may leave patients who best respond to the "losing" drug without coverage.

The report, conducted by researchers Tomas Philipson and Eric Sun of the Manhattan Institute's Project FDA, examines a CER trial for antipsychotic drugs in the Medicaid program and finds that applying restrictive reimbursement for "losing" drugs could actually reduce patient health and increase health-care costs. By limiting coverage for more expensive drugs that benefit patients outside the average, the authors find that worsened patient health would increase health-care costs by $1.3 billion, outweighing the Medicaid savings.

Dr. Philipson authored a related paper on this topic, "The Impact of Comparative Effectiveness Research on Health and Health Care Spending," that was published in the Journal of Health Economics website.

Blog Post

CER Tweets of the Week: Improving Patient Care Remains Hot Topic (July 14 - 18)

Evidence-based medicine (EBM) and the role of big data in improving patient care continued to be hot topics among comparative effectiveness research...
Blog Post

CER Tweets of the Week: Patient-Generated Data, Value-Based Payment Programs & Impact of CER (July 7 - 11)

Which issues attracted comparative effectiveness research (CER) stakeholders’ attention this week in the Twitterverse? ...
Blog Post

#TBT: Consumer-Directed Health Plans & Employers’ Decision-Making

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

CER Tweets of the Week: Evidence-Based Medicine & #PCORI Advisory Panels (June 30th – July 4th)

What was trending among comparative effectiveness research (CER) stakeholders on Twitter this week? Dialogue comparing evidence-based medicine with...
Press Release

NPC Annual Stakeholder Survey: Comparative Effectiveness Research Is Important, But Impact on Health Care Decision-Making Is Still on the Horizon

(Washington, DC, May 19, 2014)—A new survey of health care stakeholders reveals continued optimism for the use of comparative effectiveness research...
Press Release

CER Collaborative Improving Health Outcomes Through New Comparative Evidence Tools

(Washington, DC, March 24, 2014)—Three peer-reviewed articles published in Value in Health offer important guidance to aid formulary decision-makers...
Press Release

NPC, Quintiles Study Tests Tools to Evaluate Quality of Observational Research in Comparative Effectiveness Studies

(Washington, DC, February 25, 2014)—With the growing demand for information about comparative effectiveness and questions about the quality of...
Press Release

NPC, UMD Study: Factors That Cause Different Treatment Responses Are Not Well Understood or Studied

Washington, DC, November 4, 2013—Although researchers and health care providers widely recognize that individuals with stage IV prostate cancer react...
Commentary and Testimony Page

NPC Comments on CMS' Proposed Changes to Protected Classes

March 7, 2014Marilyn B. TavennerAdministratorCenters for Medicare & Medicaid ServicesU.S. Department of Health and Human Services200 Independence...
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

This month, NPC released its third annual survey on stakeholders’ views on comparative effectiveness research (CER), “The State of Comparative...
Commentary and Testimony Page

Keeping Our Eye on the CER Ball

Until the cherry blossoms begin to bloom later next month, most of the water cooler conversations in Washington will focus on the federal budget....
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
YouTube Videos

Shifting the Focus From "How Much" to "How Well" We Spend Our Health Care Dollars

A. Mark Fendrick, MD, director of the Center for Value-Based Insurance design at the University of Michigan, highlights the key findings from a...
YouTube Videos

Engaging Consumers in Today's Changing Health Care Payment and Delivery Environment

The current health care delivery system is evolving from a fee-for-service system to one that is performance-based. How does this shift impact...
YouTube Videos

CER and the Environment for Health Care Decision-Making

The National Pharmaceutical Council’s (NPC) fourth annual survey of health care stakeholders is continuing to shed light on the current environment...
Blog Post

CER Tweets of the Week: Improving Patient Care Remains Hot Topic (July 14 - 18)

Evidence-based medicine (EBM) and the role of big data in improving patient care continued to be hot topics among comparative effectiveness research...
Blog Post

CER Tweets of the Week: Patient-Generated Data, Value-Based Payment Programs & Impact of CER (July 7 - 11)

Which issues attracted comparative effectiveness research (CER) stakeholders’ attention this week in the Twitterverse? ...
Blog Post

#TBT: Consumer-Directed Health Plans & Employers’ Decision-Making

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

CER Tweets of the Week: Evidence-Based Medicine & #PCORI Advisory Panels (June 30th – July 4th)

What was trending among comparative effectiveness research (CER) stakeholders on Twitter this week? Dialogue comparing evidence-based medicine with...

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