Interested in sharing the research? You can order print copies of many research publications.

Order Reprints

Newsletter Sign-Up

Keep up to date with NPC news and events by signing up for our e-newsletter E.V.I.dently, and our CER Daily Newsfeed.

Subscribe POLICY

NEWS FEEDS

The GRACE Checklist for Rating the Quality of Observational Studies of Comparative Effectiveness: A Tale of Hope and Caution

With the growing demand for information about comparative effectiveness and questions about the quality of research that will support future health care decision-making, a group of researchers led by Quintiles and the National Pharmaceutical Council have developed and tested a checklist to evaluate the quality and usefulness of observational research studies. The Good ReseArch for Comparative Effectiveness (GRACE) checklist was published as part of a peer-reviewed study, "The GRACE Checklist for Rating the Quality of Observational Studies of Comparative Effectiveness: A Tale of Hope and Caution," that was published in the March 2014 issue of Journal of Managed Care & Specialty Pharmacy.

The GRACE checklist contains 11 items about data and research methods that can be used as an initial screening tool to separate observational studies that meet baseline quality criteria from those that do not. The GRACE checklist is “based on existing literature and guidance from experts with extensive experience in the conduct and utilization of observational comparative effectiveness research,” and is meant to help determine which observational studies should be considered to support decision-making. This checklist is an outgrowth from the GRACE Principles, a set of high-level questions that lay out the elements of good practice for the design, conduct, analysis and reporting of observational CER studies.

Blog Post

Are We Getting the Right Data to Make Individualized Health Decisions? Maybe.

Personalized medicine—an evolving field in which physicians use diagnostic tests to determine which medical treatments will work best for each...
Blog Post

NPC’s Dr. Graff on Developing Evidence That Is “Fit for Purpose”

What information do payers feel they need to guide their coverage decisions? Jennifer Graff, PharmD, vice president of comparative effectiveness...
Blog Post

Tackling Data Access at Health Datapalooza

By Jennifer Graff, PharmD, NPC VP for Comparative Effectiveness ResearchWe’re looking forward to participating in Health Datapalooza next week, which...
Newsletter Volume

E.V.I.dently: April 2016

MessageValue Assessment Through a Broader, Patient-Focused LensNPC has developed “Guiding Practices for Patient-Centered Value Assessment” to help...
Press Release

Data Can Offer Critical Insights, But Roadblocks to Data Access Persist

(Washington, D.C., April 1, 2016)—Data is key to improving health outcomes and creating efficiencies in our health care system, but a new study...
Press Release

Fit for Purpose? New NPC, AcademyHealth Framework Closes Gaps Between Payer Needs and Research Answers

(Washington, DC, September 21, 2015)—Despite multi-million dollar public and private investments to tap into big data and improve the evidence...
Press Release

NPC Comments on CMS’ Announcement to Allow Broader Access to Publicly Funded Databases

(Washington, DC, June 2, 2015)—The National Pharmaceutical Council (NPC) today commented on the Centers for Medicare and Medicaid Services’ (CMS)...
Press Release

NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making

(Washington, DC, March 26, 2015)—A new survey of health care stakeholders reveals continued optimism that comparative effectiveness research (CER)...
Commentary and Testimony Page

The Importance of Evidence, Value, Access and Innovation in 2016

Last year, in our 2015 Health Care Outlook published in Chain Drug Review, I highlighted the recent announcement by the U.S. Department of Health and...
Commentary and Testimony Page

Chain Drug Review – Commentary: “Health Care Outlook for 2015”

This commentary was originally published in the January 5, 2015 issue of Chain Drug Review.By: Dan Leonard, President, National Pharmaceutical...
Commentary and Testimony Page

Stakeholders Stand to Benefit From Better Research Methods

Stakeholders agree that good research has the potential to inform better health care decisions. But how do we define "good research?" Although...
Commentary and Testimony Page

AMCP Call for Comment on Addenda/Appendices to AMCP’s Format for Formulary Submissions Version 3.0

The National Pharmaceutical Council (NPC) welcomes the opportunity to comment on the Format addendum on Comparative Effectiveness Research (CER). As...
YouTube Videos

When Is Evidence Fit for Purpose? Closing Gaps Between Researchers, Payers

Despite multi-million dollar public and private investments to tap into big data and improve the evidence available for health care decision-making,...
YouTube Videos

Using Real-World Evidence to Increase Health Care Access, Improve Quality & Reduce Costs

Mitchell Sugarman, vice president of health economics, policy and payment at Medtronic Cardiac and Vascular Group, explains that health care decision...
YouTube Videos

Big Data: Its Evolving Use and Challenges

William Crown, PhD, chief scientific officer at Optum Labs, discusses how the use and nature of big data in health care has been evolving in recent...
YouTube Videos

Use of Big and Real-World Data by Pharma: More than Data Warehousing

Real-world data—a subset of big data—is clinical data used for decision-making that did not come from a clinical trial. According to Aaron Galaznik,...
Blog Post

Are We Getting the Right Data to Make Individualized Health Decisions? Maybe.

Personalized medicine—an evolving field in which physicians use diagnostic tests to determine which medical treatments will work best for each...
Blog Post

NPC’s Dr. Graff on Developing Evidence That Is “Fit for Purpose”

What information do payers feel they need to guide their coverage decisions? Jennifer Graff, PharmD, vice president of comparative effectiveness...
Blog Post

Tackling Data Access at Health Datapalooza

By Jennifer Graff, PharmD, NPC VP for Comparative Effectiveness ResearchWe’re looking forward to participating in Health Datapalooza next week, which...
Blog Post

Evidence Supply and Demand: A Framework for Closing Gaps between Researchers and Payers

With growing efforts and investments by stakeholders to tap into Big Data, the evidence available to inform payer decision-making, including real-...

Got CER? Educating Pharmacists for Practice in the Future: New Tools for New Challenges

This study provides an early evaluation of the CER Collaborative's training program's impact on...

Data, Data Everywhere, But Access Remains a Big Issue for Researchers

This study captures the policy inconsistencies and hurdles that can hinder use of publicly funded...

Standards and Guidelines for Observational Studies: Quality Is in the Eye of the Beholder

The lack of observational study standard/guideline agreement may contribute to variation in study...
  •  
  • 1 of 8
  • >