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International Comparison of Comparative Effectiveness Research in Five Jurisdictions: Insights for the US

This article, published in the Ocotber 2010 issue of PharmacoEconomics, examines health technology assessments (HTA) in Canada, Sweden, Scotland, The Netherlands and Australia and identifies seven shared characteristics that potentially serve as insights for development of CER in the United States. 


Among the study’s key conclusions:

  • CER should be responsive to stakeholder needs by minimizing the time to make assessments, maximizing transparency, and using a process that is fair and is conducted with universally agreed-upon standards.
  • Unlike other countries in which the HTA process assesses benefits to inform a single payer, the diverse multi-payer system in the U.S. suggests that national efforts here are best focused on generating comparative effectiveness evidence.
  • Using CER to identify therapeutic benefit among specific demographic groups (e.g., the elderly or racial and ethnic minorities) and individuals with specific genetic characteristics, disabilities, or multiple conditions may be difficult to achieve because few randomized trials can really detect differences, and thus such studies are rare.

Due to copyright issues, the article must be downloaded from the PharmacoEconomics website.

Newsletter Volume

E.V.I.dently October 2014

Message From NPCMind the Gap: Improving Quality Measurement in Accountable Care SystemsOur society is obsessed with quality, from the cars that we...
Blog Post

CER Tweets of the Week: Fendrick Elected to IOM, GAO Calls to Fill PCORI Methodology Committee Seat & More (October 20-24)

This week, comparative effectiveness research (CER) stakeholders tweeted about new appointments and open positions at top health care organizations....
Blog Post

CER Tweets of the Week: The State of Accountable Care, JAMA on PCORI’s Perspective, Real-World Impact of CER (October 13-17)

Health care stakeholders tweeted about accountable care, patient-centered outcomes research (PCOR) and the real-world impact of comparative...
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CER Tweets of the Week: Health Affairs on the High Value of Specialty Medications, Pediatric CER Guidelines, Patient Heterogeneity (October 6-10)

This week, comparative effectiveness research (CER) stakeholders tweeted articles about specialty medications, CER guidelines and individual...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

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Press Release

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CER Collaborative Improving Health Outcomes Through New Comparative Evidence Tools

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NPC, Quintiles Study Tests Tools to Evaluate Quality of Observational Research in Comparative Effectiveness Studies

(Washington, DC, February 25, 2014)—With the growing demand for information about comparative effectiveness and questions about the quality of...
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

This month, NPC released its third annual survey on stakeholders’ views on comparative effectiveness research (CER), “The State of Comparative...
Commentary and Testimony Page

Keeping Our Eye on the CER Ball

Until the cherry blossoms begin to bloom later next month, most of the water cooler conversations in Washington will focus on the federal budget....
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
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Living Up to Its Name? The Role of Patient-Centered Research

Anyone who has ever received bad news from his or her health care provider or held a loved one’s hand when a diagnosis was delivered can understand...
YouTube Videos

Health Technology Assessments and Specialty Medications

David Grainger, senior director, global public policy, Eli Lilly and Company, says that there are often challenges in conducting health technology...
YouTube Videos

Differences in Global Health Technology Assessment

David Grainger, senior director, global public policy, Eli Lilly and Company, describes how health technology assessment (HTA) informs policy and...
YouTube Videos

Incorporating Patient Views Into Health Technology Assessments

David Grainger, senior director, global public policy, Eli Lilly and Company, explains that many health technology assessments are incorporating...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
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CER Tweets of the Week: Fendrick Elected to IOM, GAO Calls to Fill PCORI Methodology Committee Seat & More (October 20-24)

This week, comparative effectiveness research (CER) stakeholders tweeted about new appointments and open positions at top health care organizations....
Blog Post

CER Tweets of the Week: The State of Accountable Care, JAMA on PCORI’s Perspective, Real-World Impact of CER (October 13-17)

Health care stakeholders tweeted about accountable care, patient-centered outcomes research (PCOR) and the real-world impact of comparative...
Blog Post

CER Tweets of the Week: Health Affairs on the High Value of Specialty Medications, Pediatric CER Guidelines, Patient Heterogeneity (October 6-10)

This week, comparative effectiveness research (CER) stakeholders tweeted articles about specialty medications, CER guidelines and individual...
Blog Post

CER Tweets of the Week: Reports on Health Care Quality, Fellowships, and PCORI Turns 4

A report on health care quality from the U.S. Department of Health and Human Services, postdoctoral fellowships and the Patient-Centered Outcomes...

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