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International Comparison of Comparative Effectiveness Research in Five Jurisdictions: Insights for the US

This article, published in the Ocotber 2010 issue of PharmacoEconomics, examines health technology assessments (HTA) in Canada, Sweden, Scotland, The Netherlands and Australia and identifies seven shared characteristics that potentially serve as insights for development of CER in the United States. 


Among the study’s key conclusions:

  • CER should be responsive to stakeholder needs by minimizing the time to make assessments, maximizing transparency, and using a process that is fair and is conducted with universally agreed-upon standards.
  • Unlike other countries in which the HTA process assesses benefits to inform a single payer, the diverse multi-payer system in the U.S. suggests that national efforts here are best focused on generating comparative effectiveness evidence.
  • Using CER to identify therapeutic benefit among specific demographic groups (e.g., the elderly or racial and ethnic minorities) and individuals with specific genetic characteristics, disabilities, or multiple conditions may be difficult to achieve because few randomized trials can really detect differences, and thus such studies are rare.

Due to copyright issues, the article must be downloaded from the PharmacoEconomics website.

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This week, comparative effectiveness research (CER) stakeholders tweeted about @AcademyHealth’s new paper comparing international efforts to boost...
Commentary and Testimony Page

Chain Drug Review – Commentary: “Health Care Outlook for 2015”

This commentary was originally published in the January 5, 2015 issue of Chain Drug Review.By: Dan Leonard, President, National Pharmaceutical...
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CER Tweets of the Week: Clinical Uncertainty in Surgery and EBM & Patient-Centered Medicine and EBM (December 29 – January 2)

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Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

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Press Release

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Press Release

CER Collaborative Improving Health Outcomes Through New Comparative Evidence Tools

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NPC, Quintiles Study Tests Tools to Evaluate Quality of Observational Research in Comparative Effectiveness Studies

(Washington, DC, February 25, 2014)—With the growing demand for information about comparative effectiveness and questions about the quality of...
Commentary and Testimony Page

Chain Drug Review – Commentary: “Health Care Outlook for 2015”

This commentary was originally published in the January 5, 2015 issue of Chain Drug Review.By: Dan Leonard, President, National Pharmaceutical...
Commentary and Testimony Page

NPC Comments on PCORI Proposal for Peer Review of Primary Research and Public Release of Research Findings

November 7, 2014Dr. Joe SelbyExecutive DirectorPatient-Centered Outcomes Research Institute1828 L St., NW, Suite 900Washington, DC 20036Dear Dr....
Commentary and Testimony Page

The State of CER and the Environment for Health Care Decision Making

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Commentary and Testimony Page

Keeping Our Eye on the CER Ball

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YouTube Videos

Health Technology Assessments and Specialty Medications

David Grainger, senior director, global public policy, Eli Lilly and Company, says that there are often challenges in conducting health technology...
YouTube Videos

Differences in Global Health Technology Assessment

David Grainger, senior director, global public policy, Eli Lilly and Company, describes how health technology assessment (HTA) informs policy and...
YouTube Videos

Incorporating Patient Views Into Health Technology Assessments

David Grainger, senior director, global public policy, Eli Lilly and Company, explains that many health technology assessments are incorporating...
YouTube Videos

Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice

National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, discusses a peer-reviewed study suggesting that changes are needed...
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CER Tweets of the Week: The Challenges of Gray-Zone Medicine, PCORI in the Congress Blog (January 12-16)

This week, comparative effectiveness research (CER) stakeholders tweeted multiple articles regarding CER and various challenges they face. They...
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CER Tweets of the Week: Clinical Uncertainty in Surgery and EBM & Patient-Centered Medicine and EBM (December 29 – January 2)

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CER Tweets of the Week (December 22-26): PCORI Offers Up to $150.7 Million to Support PCORnet Phase II; Views on Evidence-Based Medicine

In addition to sharing the latest news about the Patient-Centered Outcomes Research Institute’s latest grants and PCORnet, comparative effectiveness...

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Commentary & Testimony