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Racial and Ethnic Differences in Response to Medicines: Towards Individualized Pharmaceutical Treatment

Recognizing that substantial disparities exist in the quality and quantity of medical care received by minority Americans, especially those of African, Asian and Hispanic heritage, this article reviews the genetic factors that underlie varying responses to medicines observed among different ethnic and racial groups. Pharmacogenetic research in the past few decades has uncovered significant differences among racial and ethnic groups in the metabolism, clinical effectiveness, and side-effect profiles of many clinically important drugs. The authors suggest that these differences must be taken into account in the design of cost management policies such as formulary implementation, therapeutic substitution and step-care protocols. They also suggest that these programs should be broad and flexible enough to enable rational choices and individualized treatment for all patients, regardless of race or ethnic origin.

Blog Post

#TBT: Why Patient Differences Matter, Especially When It Comes to Cancer Treatments

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
YouTube Videos

Why are quality measures important? We asked health care thought leaders to tell us why.

Quality measurement, tied to financial incentives, is one of many approaches accountable care programs are using to promote system-wide improvement....
Newsletter Volume

E.V.I.dently September 2014

Message From NPCPatient Access to Medicines: A Growing ChallengeFor health care consumers, the rationale for why some medicines are covered by their...
Blog Post

#TBT: Senior Citizens Day & Individualized Pharmaceutical Care

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Press Release

Michael Ciarametaro Joins National Pharmaceutical Council as Director of Research

WASHINGTON, DC (July 31, 2014)—The National Pharmaceutical Council (NPC) today announced that Michael Ciarametaro has joined the health policy...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

Washington, DC (July 29, 2014)—New research led by the National Pharmaceutical Council (NPC) can assist health care stakeholders to understand when...
Press Release

Specialty Medications: Shifting the Focus From “How Much” We Spend to “How Well” We Spend

Washington, DC, June 9, 2014—As health care decision-makers grapple with how to ensure access to specialty medications, the University of Michigan...
Press Release

NPC, UMD Study: Factors That Cause Different Treatment Responses Are Not Well Understood or Studied

Washington, DC, November 4, 2013—Although researchers and health care providers widely recognize that individuals with stage IV prostate cancer react...
Commentary and Testimony Page

NPC Comments on CMS' Proposed Changes to Protected Classes

March 7, 2014Marilyn B. TavennerAdministratorCenters for Medicare & Medicaid ServicesU.S. Department of Health and Human Services200 Independence...
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
Commentary and Testimony Page

The Risks of Standardized Health Care

Think about the last time you visited a medical office. Even at a specialist’s office, chances are that each person waiting for his or her name to be...
Commentary and Testimony Page

Framework Helps ACOs Leverage Pharmaceuticals to Realize Quality, Cost Goals

Medications are more than an item on the balance sheet for health care providers. Pharmaceuticals offer a route to manage costs while achieving...
YouTube Videos

Why are quality measures important? We asked health care thought leaders to tell us why.

Quality measurement, tied to financial incentives, is one of many approaches accountable care programs are using to promote system-wide improvement....
YouTube Videos

Using Distributed Data Networks to Understand Heterogeneity in Real-World Data

Kimberly Westrich, director of health services research at the National Pharmaceutical Council, explains how large observational datasets like...
YouTube Videos

Taking Patient Variations Into Account

Dr. Lisa Egbuonu-Davis, founder of ROI Squared, explains that data is generally designed toward looking at the mean differences instead of the...
YouTube Videos

Understanding Individual Patients' Health Care Needs

Paul Martino, SVP of Clinical Strategy and Innovation at WellPoint, Inc., explains that it's important for payers and other health care stakeholders...
Blog Post

#TBT: Why Patient Differences Matter, Especially When It Comes to Cancer Treatments

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

#TBT: Senior Citizens Day & Individualized Pharmaceutical Care

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

#TBT: Ethnic Disparities in the Burden and Treatment of Asthma

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

NPC to Discuss Role of Pharmaceuticals, Applying Real-World Evidence at ISPOR Annual Meeting

Planning to attend the International Society for Pharmacoeconomics and Outcomes Research’s (ISPOR) 19th Annual International Meeting in Montreal May...

Research

JCER

The Emerging Relevance of Heterogeneity of Treatment Effect in Clinical Care: A Study Using Stage IV Prostate Cancer as a Model

Although researchers and health care providers widely recognize that individuals with stage IV...
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Commentary & Testimony