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Racial and Ethnic Differences in Response to Medicines: Towards Individualized Pharmaceutical Treatment

Recognizing that substantial disparities exist in the quality and quantity of medical care received by minority Americans, especially those of African, Asian and Hispanic heritage, this article reviews the genetic factors that underlie varying responses to medicines observed among different ethnic and racial groups. Pharmacogenetic research in the past few decades has uncovered significant differences among racial and ethnic groups in the metabolism, clinical effectiveness, and side-effect profiles of many clinically important drugs. The authors suggest that these differences must be taken into account in the design of cost management policies such as formulary implementation, therapeutic substitution and step-care protocols. They also suggest that these programs should be broad and flexible enough to enable rational choices and individualized treatment for all patients, regardless of race or ethnic origin.

Blog Post

ASCO’s Clinical Pathways Recommendations and Remaining Challenges

The American Society of Clinical Oncology (ASCO) today released its “policy statement on clinical pathways in oncology,” which acknowledges the...
YouTube Videos

Anthem's Dr. Malin on Care Pathways: Their Implementation and Evaluation

Dr. Jennifer Malin, medical director, oncology and care management, Anthem, Inc., explains that her organization uses care pathways to address the...
YouTube Videos

Anthem's Dr. Malin on Clinical Care Pathways and Innovation

Could clinical care pathways help innovation? Anthem Inc.'s Dr. Jennifer Malin, medical director, oncology and care management, says it’s a strong...
YouTube Videos

Anthem's Malin: Communication Is Key to Success of Care Pathways

To make a clinical care pathway successful, “you have to work on many levels to engage providers,” says Dr. Jennifer Malin, medical director,...
Press Release

Michael Ciarametaro Joins National Pharmaceutical Council as Director of Research

Washington, DC (July 31, 2014)—The National Pharmaceutical Council (NPC) today announced that Michael Ciarametaro has joined the health policy...
Press Release

NPC Study Outlines When & How Health Decision-Makers Should Consider Individual Patient Differences

Washington, DC (July 29, 2014)—New research led by the National Pharmaceutical Council (NPC) can assist health care stakeholders to understand when...
Press Release

Specialty Medications: Shifting the Focus From “How Much” We Spend to “How Well” We Spend

Washington, DC, June 9, 2014—As health care decision-makers grapple with how to ensure access to specialty medications, the University of Michigan...
Press Release

NPC, UMD Study: Factors That Cause Different Treatment Responses Are Not Well Understood or Studied

Washington, DC, November 4, 2013—Although researchers and health care providers widely recognize that individuals with stage IV prostate cancer react...
Commentary and Testimony Page

Chain Drug Review – Commentary: “Health Care Outlook for 2015”

This commentary was originally published in the January 5, 2015 issue of Chain Drug Review.By: Dan Leonard, President, National Pharmaceutical...
Commentary and Testimony Page

NPC Comments on CMS' Proposed Changes to Protected Classes

March 7, 2014Marilyn B. TavennerAdministratorCenters for Medicare & Medicaid ServicesU.S. Department of Health and Human Services200 Independence...
Commentary and Testimony Page

Leveling the Playing Field? Could a Landmark Decision Alter the CER Communications Landscape?

A growing chorus of voices is publicly sharing data on the effectiveness of treatment options, but one viewpoint has long been shut out of key areas...
Commentary and Testimony Page

The Risks of Standardized Health Care

Think about the last time you visited a medical office. Even at a specialist’s office, chances are that each person waiting for his or her name to be...
YouTube Videos

Anthem's Malin: Having Patient-Level Data Can Improve Clinical Care Pathways

The success of a clinical care pathway is related to the breadth and quality of the information that is available to organizations developing...
YouTube Videos

Anthem's Dr. Malin on Care Pathways: Their Implementation and Evaluation

Dr. Jennifer Malin, medical director, oncology and care management, Anthem, Inc., explains that her organization uses care pathways to address the...
YouTube Videos

Anthem's Dr. Malin on Clinical Care Pathways and Innovation

Could clinical care pathways help innovation? Anthem Inc.'s Dr. Jennifer Malin, medical director, oncology and care management, says it’s a strong...
YouTube Videos

Anthem's Malin: Communication Is Key to Success of Care Pathways

To make a clinical care pathway successful, “you have to work on many levels to engage providers,” says Dr. Jennifer Malin, medical director,...
Blog Post

ASCO’s Clinical Pathways Recommendations and Remaining Challenges

The American Society of Clinical Oncology (ASCO) today released its “policy statement on clinical pathways in oncology,” which acknowledges the...
Blog Post

#TBT: 10 Prescribing Principles for Older Patients & #WHCOA

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

#TBT: Men’s Health Month & Differences in Prostate Cancer Treatment

As part of our “Throwback Thursday” blog series, we’re taking a look at a topic that’s currently in the news and tagging it with previous...
Blog Post

Biodiversity and Health Care Quality: The 21st Century Challenge

Minorities comprise a growing segment of the U.S. population, but accounting for biodiversity and quality in health care remain significant...

Exploration of Heterogeneity in Distributed Research Network Drug Safety Analyses

Distributed data network drug safety analyses are di

Ethnic Disparities in the Burden and Treatment of Asthma

This report, developed in partnership with the

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