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The National Pharmaceutical Council (NPC) is a health policy research organization dedicated to the advancement of good evidence and science, and to fostering an environment in the United States that supports medical innovation.
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Showing 79 Results
Individual Treatment Effects: Implications for Research, Clinical Practice, and Policy
This research outlines a framework and policy considerations to help health care stakeholders understand when it is important take patients’ individual treatment responses into account when making…
Real-World Impact of Comparative Effectiveness Research Findings on Clinical Practice
This study suggests that changes are needed to enable more consistent translation of research findings into clinical practice.
Supporting Consumer Access to Specialty Medications Through Value-Based Insurance Design
Value-based insurance design (V-BID) is a key tactic payers and purchasers can use to promote access to high-value specialty medications.
The Good, the Bad, and the Different: A Primer on Aspects of Heterogeneity of Treatment Effects
The concept of heterogeneity is explained and further explored via four articles published in the June 2014 issue of the Journal of Managed Care & Specialty Pharmacy: The Good, the Bad, and the…
CER Collaborative: Series of Questionnaires to Guide Decision-makers in Reviewing Studies
Three peer-reviewed articles offer important guidance to aid formulary decision-makers in evaluating certain types of comparative effectiveness research (CER) studies.
The GRACE Checklist for Rating the Quality of Observational Studies of Comparative Effectiveness: A Tale of Hope and Caution
With the growing demand for information about comparative effectiveness and questions about the quality of research that will support future health care decision-making, a group of researchers…
The Emerging Relevance of Heterogeneity of Treatment Effect in Clinical Care: A Study Using Stage IV Prostate Cancer as a Model
Although researchers and health care providers widely recognize that individuals with stage IV prostate cancer react differently to treatments, the factors that impact treatment outcomes, including…
2013 Comparative Effectiveness Research and the Environment for Health Care Decision-Making
The National Pharmaceutical Council conducted its third annual survey of key health care stakeholders. The purpose was to set a baseline for where key stakeholders believe we are today on comparative…
Communicating About Comparative Effectiveness Research: A Health Affairs Symposium on the Issues
One of many issues connected with comparative effectiveness research is how the findings will be communicated, particularly if they pertain to prescription drugs and if the findings could be useful…
Principles for Planning and Conducting Comparative Effectiveness Research
A group of researchers developed a set of 13 best practice principles for comparative effectiveness research. The 13 principles were published as part of a peer-reviewed study in the September 2012…
A Translation Table for Patient-Centered Comparative Effectiveness Research-- Guidance to Improve the Value of Research for Clinical and Health Policy Decision-Making
This collaborative project was developed by the National Pharmaceutical Council, the Center for Medical Technology Policy, and Outcome, a Quintiles Company.
Three Perspectives on the Impact of Comparative Effectiveness Research on Decision Making
In a special supplement to the May 2012 Journal of Managed Care Pharmacy, National Pharmaceutical Council Chief Science Officer Robert W. Dubois, MD, PhD, takes a closer look at comparative…
Making Informed Decisions: Assessing the Strengths and Weaknesses of Study Designs and Analytic Methods for Comparative Effectiveness Research
The purpose of this document is to provide brief descriptions of both experimental and nonexperimental study designs and methods that may be used to address CER study questions.
Comparative Effectiveness Research: Do Employers Care? What Will They Do? What About Productivity?
A survey by NPC and the Benfield Group found that one of the benefits employers are looking for from CER is more information about which treatments help with productivity.
Toward individualized pharmaceutical care of East Asians: the value of genetic testing for polymorphisms in drug-metabolizing genes
Research considers how genetics can impact how well medicines will work in certain populations.