News from Wednesday, November 20, 2024
Articles
OS Better With Belantamab Mafodotin Triplet vs Daratumumab in R/R MM
(11/19, Jordyn Sava, The American Journal of Managed Care) reports “The DREAMM-7 trial showed belantamab mafodotin combination significantly improved overall survival in relapsed/refractory multiple myeloma compared to daratumumab-based therapy. The investigational arm demonstrated superior progression-free survival and overall response rates, despite higher adverse event rates.” Full
With RFK Jr. Looming as Health Secretary, Pharma Execs Try to Project Stability
(11/19, Andrew Joseph, STAT Plus) reports “...Overall, the incoming Trump administration will likely be friendly to corporate interests, as the first Trump presidency was. Vivek Ramaswamy, a biotech veteran who has his own views on changing how the Food and Drug Administration regulates medicines, is also a close Trump adviser. Some pharma executives, when asked about Trump winning another term, have said they worked well with the first Trump administration.” Subscription Required
Prior Authorization Is Changing. Providers Say It's Not Enough
(11/20, Bridget Early, Modern Healthcare) reports “...CMS proposed a rule that would have required providers and insurers to use a specific set of electronic data-sharing standards for prior authorizations, claims reviews and electronic attachments. But AHIP, the American Hospital Association, American Medical Association, and the Blue Cross Blue Shield Association jointly called on CMS to rethink its proposals, which they said would create a mismatch between two regulations and worsen interoperability problems rather than fixing them.” Subscription Required
Press Releases
Research from COTA and Leading Global Cancer Center Demonstrate How Real-World Data Can Fill Cancer Care Gaps for Older Patients
(11/20, COTA Press Release) “...‘The incorporation of real-world data to assess outcomes in older patients is an invaluable resource, given their general decreased representation in clinical trials. The data being presented at ASH 2024 regarding the DTI interval (Diagnosis to Treatment Interval) and the utilization of hospice/palliative care referrals can help inform future trials and identifies ongoing gaps in our knowledge/practices,’ noted Paul A. Hamlin, MD, Medical Director, David H. Koch Center for Cancer Care, and Attending, Lymphoma Service - Division of Hematologic Malignancies at MSK.” Full
Journals
Comparative Effectiveness of High-Efficacy and Moderate Efficacy Disease-Modifying Agents in Reducing the Annualized Relapse Rates Among Multiple Sclerosis Patients in the United States
Jieni Li, et al.
November 16, 2024, Preventive Medicine
Untapped Potential? Representativeness in Pragmatic Clinical Trials
Caleigh Propes, BA; Kayla Mehl, PhD; Stephanie R. Morain, PhD, MPH
November 20, 2024, JAMA
Events
Webinar: EU HTA – Achieving Broad Access Fast! What Will it Take for Innovative Medicines to Succeed?
December 3, 2024
10:30AM EST