News from Friday, January 3, 2025
Articles
Study Compares Single-Inhaler Triple Therapies for Treatment of COPD
(1/3, Elana Gotkine, Medical Xpress) reports “For patients with chronic obstructive pulmonary disease (COPD), budesonide-glycopyrrolate-formoterol does not improve clinical outcomes compared with fluticasone-umeclidinium-vilanterol, according to a study published online Dec. 30 in The BMJ.” Full
250 Brand Drugs To See Average Of 4.5% Price Hikes, Advocates Urge Congress To Act
(1/2, Gabrielle Wanneh, Inside Health Policy) reports “...The [Campaign for Sustainable Rx Pricing’s] solutions range from Congress passing bills to prohibit drug makers from placing so-called patent thickets on a single product to extend its market exclusivity and to promote the use of biosimilars as a substitute to higher-cost brand biologics; empowering the Patient-Centered Outcomes Research Institute and Agency for Healthcare Research and Quality with the resources and authorities necessary to conduct assessments of the affordability of launch prices and annual price increases...” Subscription Required
UK: Man's Anxious Wait for MND Drug Approval
(½, Catriona Aitken, BBC) reports “...Tofersen is suitable for 2% of people with [motor neurone disease], or about 100 people across Wales and England and was previously considered by NICE as too costly for the NHS. But, following a charity campaign, NICE announced it would reconsider its approach to the drug to look at it as part of the Highly Specialised Technologies (HST) programme, for the most rare and severe diseases.” Full
Journals
Comparative Effectiveness and Safety of Single Inhaler Triple Therapies for Chronic Obstructive Pulmonary Disease: New User Cohort Study
William B Feldman, et al.
December 30, 2024, BMJ
Effectiveness and Safety of Treatments for Early-Stage Merkel Cell Carcinoma: A Systematic Review and Meta-Analysis of Randomized and Non-Randomized Studies
Yves Paul Vincent Mbous, et al.
January 2025, Cancer Medicine
Effectiveness of Tacrolimus Therapy in Refractory Ulcerative Colitis Compared to Infliximab with Propensity Score Matching
Takeo Yoshihara, et al.
January 2, 2025, Scientific Reports
Evaluating Generalizability of Oncology Trial Results to Real-World Patients Using Machine Learning-Based Trial Emulations
Xavier Orcutt, et al.
January 3, 2025, Nature Medicine