News from Thursday, February 6, 2025
Articles
Mirikizumab Demonstrates Superior Maintenance Efficacy in UC Treatment
(2/6, Skylar Jeremias, The American Journal of Managed Care) reports “Mirikizumab demonstrated superior maintenance efficacy over most therapies used to treat ulcerative colitis (UC), according to a Bayesian network meta-analysis to compare the efficacy and safety of biologics and small molecules for treating moderately to severely active UC.” Full
Flatiron Health and Exact Sciences Partner to Accelerate Clinical Evidence Generation for MRD Testing in Oncology
(2/5, Fred Pennic, HIT Consultant) reports “...The collaboration will leverage Flatiron’s innovative clinical research platform and extensive network of community oncology practices to study the test’s performance in diverse patient populations and real-world settings.” Full
Seizing Intellectual Property for Medicines Is Not a Path to Prosperity
(2/5, Kirsten Axelsen, Peter Pitts, AEI) comments “Since healthcare is among the biggest costs to the federal government, it is reasonable to evaluate what is spent on medical care and to consider policies and regulations to root out waste. However, the re-emergence of proposals to take away intellectual property for drugs is counterproductive; they do not reduce costs, and invoking these policies would inform investors in a leading US industry, that they should find a better place for their money.” Full
Press Releases
Institute for Clinical and Economic Review Publishes Evidence Report on Treatment for Acute Pain
(2/5, ICER Press Release) “The Institute for Clinical and Economic Review (ICER) today posted its revised Evidence Report assessing the comparative clinical effectiveness and value of suzetrigine (Vertex Pharmaceuticals) for the treatment of acute pain.” Full
Institute for Clinical and Economic Review Releases Draft Evidence Report on Treatment for Advanced Retinitis Pigmentosa
(2/6, ICER Press Release) “The Institute for Clinical and Economic Review (ICER) today released a Draft Evidence Report assessing the comparative clinical effectiveness and value of sonpiretigene isteparvovec (Nanoscope Therapeutics) for the treatment of advanced retinitis pigmentosa.” Full
Journals
The Healthcare Integrated Research Database (HIRD) as a Real-World Data Source for Pharmacoepidemiologic Research
John J Barron, et al.
February 2025, Pharmacoepidemiology and Drug Safety
Real-World Effectiveness of Sotrovimab in Ambulatory Patients With COVID-19: A Retrospective Cohort Study Using a Large Administrative Claims Database in the United States
Christopher F Bell, et al.
February 4, 2025, Clinical Therapeutics