CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Friday, July 18, 2025

Articles

Value Viewpoint: July 18, 2025

(7/18, Kimberly Westrich, LinkedIn) comments “...On Thursday, ICER posted its revised Evidence Report assessing the comparative clinical effectiveness and value of nusinersen, onasemnogene abeparvovec-xioi, and risdiplam for spinal muscular atrophy (SMA), and the comparative clinical effectiveness and value of apitegromab for SMA...On Tuesday, ICER released its Final Evidence Report assessing the comparative clinical effectiveness and value of tolebrutinib for the treatment of secondary progressive multiple sclerosis (SPMS).” Full

New Blueprint Guides Patient-Centered Research for More Equitable Health Care

(7/17, Cameron Santoro, The American Journal of Managed Care) reports “...The Blueprint is intended to drive long-term change in how evidence is generated, evaluated, and applied in health care policy and practice, and it offers a shared foundation for inclusive, multistakeholder collaboration. ‘By centering patient priorities and experiences, we can create more relevant, trustworthy, and equitable evidence to inform health care decisions,’ [Center for Innovation & Value Research chief science officer Rick Chapman, PhD] concluded.” Full

Center for Innovation & Value Research Blueprint Aims to Embed Patient Perspectives Across Healthcare Research and Decision-Making

(7/17, Katie McCool, The Evidence Base) reports “...By providing a common reference point, the Blueprint supports more consistent and inclusive collaboration among stakeholders. According to the Center, it is intended to serve both as a foundational resource and a roadmap for advancing methods and tools in patient-centered value research.” Full

Video: Redefining Value: What Payers Want From Comprehensive MS Treatments

(7/18, Ryan Haumschild, PharmD, MS, MBA, CPEL, Kavita V. Nair, PhD, FAAN, The American Journal of Managed Care) “Panelists discuss how payers can evaluate BTK inhibitors by considering specific MS phenotypes and FDA indications rather than applying traditional step therapy protocols that may delay optimal treatment.” View Video

UK: NICE Recommends BeOne’s Brukinsa to Treat Mantle Cell Lymphoma on NHS

(7/18, Emily Kimber, PMLiVE) reports “The National Institute for Health and Care Excellence (NICE) has recommended BeOne Medicines’ targeted cancer drug Brukinsa (zanubrutinib) to treat certain cases of mantle cell lymphoma (MCL). The health technology assessment agency has recommended that the drug be used on the NHS in England and Wales as a treatment option for adults with relapsed or refractory MCL who have received at least one prior line of therapy.” Full

Press Releases

Institute for Clinical and Economic Review Publishes Evidence Report on Treatments for Spinal Muscular Atrophy

(7/17, ICER Press Release) “The Institute for Clinical and Economic Review (ICER) today posted its revised Evidence Report assessing the comparative clinical effectiveness of nusinersen (Spinraza®, Biogen), onasemnogene abeparvovec-xioi (Zolgensma®, Novartis), and risdiplam (Evrysdi®, Genentech) for spinal muscular atrophy (SMA). ICER is also assessing the comparative clinical effectiveness and value of apitegromab (Scholar Rock Holdings) for SMA.” Full

Journals

Cost-per-Response of Acthar Gel Versus Standard of Care for the Treatment of Noninfectious Keratitis: A United States Healthcare Perspective

Jas Bindra, et al.

July 17, 2025, Journal of Comparative Effectiveness Research

Journal of Comparative Effectiveness Research

Heterogeneity of Cardiovascular Effects of Second-Line Glucose-Lowering Therapies in Adults With Type 2 Diabetes Across the Range of Moderate Baseline Cardiovascular Risk

Yihong Deng, et al.

July 17, 2025, Journal of the American Heart Association

PubMed

Trends in Physician Exit From Fee-for-Service Medicare

Hannah T. Neprash, PhD; Michael E. Chernew, PhD

July 18, 2025, JAMA Health Forum

JAMA Health Forum

The Potential Gains of Replenishing the Global Fund

Joseph L Dieleman

July 19, 2025, The Lancet

The Lancet

Reports

Therapies for Spinal Muscular Atrophy: Effectiveness and Value

July 17, 2025

ICER