CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Tuesday, August 12, 2025

Articles

Video: Academic–Community Partnerships and Real-World Data in Value-Based Oncology: Jason Bergsbaken, PharmD, MBA, BCOP

(8/12, Jason Bergsbaken, PharmD, MBA, BCOP, Alana Hippensteele, MA, The American Journal of Managed Care) “Jason Bergsbaken, PharmD, MBA, BCOP, highlights the growing role of real-world data in validating or de-implementing therapies, the need for vigilant postapproval outcomes monitoring, and the value of academic–community oncology partnerships.” View Video

Drug Price Negotiations Pose Ruinous, Unconstitutional Dangers

(8/12, Daniel Troy, Bloomberg Law) comments “...These negotiations should be recognized as a sham. Pharmaceutical innovators are forced, under threat of financial penalties as high as 1,900% of daily revenue from all sources, to sell their patented medicines at government-dictated prices. This isn't bargaining-it's a coercive regime of price control masquerading as negotiation.” Subscription Required

Why Chiesi’s Raxone Faced a Decade-Long Wait For English Funding

(8/12, Eliza Slawther, Pink Sheet) reports “...Chiesi’s orphan drug Raxone has secured an English funding recommendation for the treatment of Leber's hereditary optic neuropathy, a decade after the orphan drug was approved for marketing. Chiesi told the Pink Sheet about its ‘long, and often challenging’ road to reimbursement.” Subscription Required

Press Releases

Patient-Centered Outcomes Issue of The American Journal of Gastroenterology Amplifies Patient Voices

(8/12, American College of Gastroenterology Press Release) “The August special issue of The American Journal of Gastroenterology focuses on patient-centered outcomes, highlighting and amplifying patient voices directly through studies, editorials, and commentaries. ‘We believe that eliciting patient-centered outcomes and how differing groups of patients experience symptoms can enhance clinician insight into the disease process, improve acceptance and adherence on therapies, and potentially increase control of the underlying disease,’ write Co-Editors-in-Chief Jasmohan S. Bajaj, MD, MS, FACG, and Millie D. Long, MD, MPH, FACG, in an editorial.” Full

Journals

Comparative Effectiveness of Bupivacaine and Lidocaine-Bupivacaine Mixtures in Brachial Plexus Block: A Systematic Review and Meta-Analysis

João M Cansian, et al.

July 2025, Anesthesia and Pain Medicine

PubMed

Carvedilol vs. Metoprolol Effectiveness in Patients With Left Ventricular Assist Devices: A TriNetX Analysis

Karldon I Nwaezeapu, et al.

July 10, 2025, Cureus

PubMed

Comparative Effectiveness of Dual Antiplatelet Therapy Versus Single Antiplatelet Therapy in Patients With Acute Stroke

Awais Aslam, et al.

July 10, 2025, Cureus

PubMed

Comparative Improvement in Health-Related Quality of Life With Advanced Therapies for Moderate-to-Severe Crohn's Disease: A Network Meta-Analysis

Olivera, Pablo A. MD, MSc, et al.

August 2025, The American Journal of Gastroenterology

The American Journal of Gastroenterology

The Role of Patient-Reported Outcomes in Cirrhosis

Desai, Archita P. MD, et al.

August 2025, The American Journal of Gastroenterology

The American Journal of Gastroenterology

Distributional Cost-Effectiveness Analysis and Health Technology Assessment at NICE: A Response to Ramagopalan

James Koh, PhD, et al.

August 12, 2025, Value in Health

Value in Health