CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Thursday, August 14, 2025

Articles

Access to Fair Prescription Plans Can Make Employees Healthier

(8/14, Bruce Sherman, Brian Sils, Kimberly Westrich, Benefits Pro) comments “...Improving the management of chronic conditions can help organizations manage their health benefits expenditures. This is particularly true for conditions including diabetes, hypertension, and high cholesterol. Poorly managed conditions are associated with a greater risk of complications, including heart and vascular disease, as well as stroke and kidney disease. An equitable approach to prescription medication use — or pharmacoequity — can help minimize the risk of these complications, resulting in likely improvements in both employee health and business outcomes.” Full

OM1 Expands Neurology Network to Over 3 Million Patients for Real-World Data Research

(8/14, Katie McCool, The Evidence Base) reports “...‘Expanding our neurology network to more than 3 million patients represents a pivotal milestone in enabling better outcomes for neurology patients,’ said Dr Carl Marci, Chief Clinical Officer and Managing Director of Mental Health and Neuroscience at OM1. ‘By integrating deep clinical data and advanced AI, we’re equipping researchers and healthcare providers with powerful tools to uncover new insights into disease progression, treatment response, and more personalized care in complex neurological conditions.’” Full

Video: Optimizing Oncology Care Through Academic–Community Partnerships and Real-World Evidence: Clayton Irvine, PharmD, MBA, MS

(8/13, Clayton Irvine, PharmD, MBA, MS, Alana Hippensteele, MA, The American Journal of Managed Care) “Clayton Irvine, PharmD, MBA, MS, explains that leveraging high-quality, real-world data; cross-institutional collaboration; standardized care pathways; advanced technologies; and integrated academic–community oncology partnerships can improve treatment decision-making, reduce financial toxicity, address drug shortages, and optimize infusion center efficiency.” View Video

CMMI Addresses Some Democratic WISeR Model Worries In FAQ, Comments

(8/13, Christian Robles, Inside Health Policy) reports “...CMS plans to audit WISeR model participants, which will result in reduced payment adjustments for inaccurate determinations, the FAQ says. Model participants with a high inaccuracy rate could be terminated from the model, the FAQ adds. Model participants will pay for processing prior authorization requests and will only be reimbursed once per Medicare beneficiary, the FAQ says. In addition to these safeguards, a source familiar with the WISeR model told Inside Health Policy that CMS’ chief actuary will have to independently evaluate and certify the model before it is expanded. The evaluation would explore whether WISeR improves quality without increasing spending or reduces spending without harming quality, they said.” Subscription Required

Press Releases

Final Decision on Cerliponase Alfa for Batten Disease Treatment Confirmed

(8/14, NICE Press Release) “In final draft guidance published today we've confirmed that we’re unable to recommend cerliponase alfa (also called Brineura and made by BioMarin) for routine NHS use in treating neuronal ceroid lipofuscinosis type 2 (CLN2), a rare and life-limiting form of Batten disease.” Full

Journals

Comparative Effectiveness of Fluid Resuscitation Strategies for Preventing Acute Kidney Injury in Critically Ill Patients: A Meta-Analysis

Ihtesham Shafiq, et al.

August 14, 2025, Cureus

Cureus

Evaluation of the Efficacy and Cost-Effectiveness of Safinamide Versus Rasagiline: A Systematic Review

Antonio J García Ruiz, et al.

August 14, 2025, Journal of Comparative Effectiveness Research

Journal of Comparative Effectiveness Research