News from Tuesday, August 26, 2025
Articles
Canadian RWE Shows Comparable Outcomes Between Etanercept Biosimilars, Originator
(8/26, Skylar Jeremias, The Center for Biosimilars) reports “As the US continues to wait for etanercept biosimilars to be allowed entrance into the market, a new Canadian analysis using real-world evidence (RWE) found no meaningful differences in remission outcomes between individuals with rheumatoid arthritis (RA) initiating etanercept biosimilars and those starting the reference product.” Full
Lubiprostone Linked With Better Kidney Function Protection in CKD With Constipation
(8/26, Jessica Nye, PhD, Renal & Urology News) reports “The risk for kidney function decline may be lower with use of lubiprostone vs stool softeners in patients with chronic kidney disease (CKD) and constipation, according to results from an observational study published in the Clinical Journal of the American Society of Nephrology.” Full
Press Releases
Evidence, Not Ideology, must Guide Preventive Health Care, Say Experts
(8/25, Canadian Medical Association Journal Press Release) “A recent review of the Canadian Task Force on Preventive Health Care underscores the need for expert bodies to produce evidence-based guidance and that Canada should ensure a renewed task force is adequately funded and supported, argues a commentary in the Canadian Medical Association Journal...‘Our review affirmed that we need expert bodies like the task force, now more than ever, to produce evidence-based guidance for the public, health care practitioners, and health systems,’ writes [Dr. Vivek Goel].” Full
Journals
Comparative Effectiveness of Lubiprostone and Stool Softeners on Risk of Kidney Outcomes in Patients with CKD
Sumida, Keiichi, et al.
July 2025, Clinical Journal of the American Society of Nephrology
Clinical Journal of the American Society of Nephrology
Disease Remission and Sustained Remission after Etanercept Biosimilar or Originator Initiation in Rheumatoid Arthritis: An Interim Real-World Analysis
Marina G. Birck, et al.
July 17, 2025, Arthritis Research & Therapy
Comparative Effectiveness and Safety of Sodium-Glucose Cotransporter 2 Inhibitors vs Glucagon-Like Peptide 1 Receptor Agonists in Elderly Patients with Type 2 Diabetes Mellitus: A Meta-Analysis
Yao Wang, et al.
August 25, 2025, Frontiers in Endocrinology
Comparative Effectiveness of Pharmacogenomic-Guided Versus Unguided Antidepressant Treatment in Major Depressive Disorder: New Insights from Subgroup and Cumulative Meta-Analyses
Yuan Zhang, et al.
August 25, 2025, BMJ Mental Health
Viscoelastic Testing in Postpartum Obstetric Hemorrhage: A Scoping Review Commissioned by the Patient Centered Outcomes Research Institute (PCORI)
C. Janzen, et al.
August 25, 2025, International Journal of Obstetric Anesthesia
International Journal of Obstetric Anesthesia
Evidence, Not Ideology, must Guide Preventive Health Care Policy Recommendations
Vivek Goel
August 25, 2025, Canadian Medical Association Journal
How Policymakers Value End-of-Life Treatments for Rare and Common Diseases in China: Evidence from a Contingent Valuation Study
Han Cheng, et al.
August 26, 2025, Global Health Research and Policy
Global Health Research and Policy
Real-World Effectiveness of Rebamipide on Gastritis Symptoms: A Patient-Focused Approach
Hyun Ji Woo, et al.
September 2025, Clinical and Translational Science