CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Wednesday, November 19, 2025

Articles

Omnichannel: Redesigning Customer Engagement to Improve Patient Outcomes

(11/19, Shontelle Dodson, PharmaPhorum) comments “...An effective Medical Affairs omnichannel approach is based on identifying knowledge and data gaps, and creating integrated evidence dissemination plans to address them. Begin with evidence generation and disclosure, work across teams to generate data, and share it through scientific congresses and publications. To ensure that information reaches healthcare professionals globally in a timely manner, amplification is also a key component. When thinking about amplification, it is critical to start by understanding what information the customer wants and the preference for receiving it.” Full

Real-World Data Show Tirzepatide and Semaglutide Offer Comparable Cardiovascular Protection

(11/19, Katie McCool, The Evidence Base) reports “...A new study from Mass General Brigham using real-world data (RWD) provides the first direct comparison of tirzepatide and semaglutide for cardiovascular protection in clinical practice. The findings, published simultaneously in Nature Medicine and presented at the American Heart Association Scientific Sessions 2025, suggest that both GLP-1–based therapies reduce major cardiovascular events in patients with type 2 diabetes and elevated cardiovascular risk.” Full

Medicare ACOs In 2024: Increased Participation And Evolving Policy Impacts

(11/19, Audrey Ford, Kylie Brown, David Muhlestein, Robert S. Saunders, Mark B. McClellan, Frank McStay, Health Affairs Forefront) comments “...Low-revenue and physician-led ACOs are more likely to earn savings compared to hospital-led ACOs, and a bump in low-revenue ACO participation in 2024 likely contributed to the higher total savings for the year. It should be noted that stakeholders have raised concerns with the specificity of the revenue status designation, with some calling for its reform. Additionally, strong savings were likely supported by increases in safety net providers, consistent with recent findings on health centers’ ability to serve more beneficiaries who are members of socially disadvantaged populations, without increasing costs or decreasing quality.” Full

AcademyHealth Joins Forces with Leading U.S. Biotech Company to Close Gap Between Research and Real-World Care

(11/19, AcademyHealth Blog) comments “Despite decades of medical progress, research shows it takes an average of 17 years for proven health innovations to be widely adopted in clinical practice and fewer than 20 percent of effective interventions ever make it that far. To change that, AcademyHealth, with support from Amgen, is launching the Applied Implementation Science Fellowship Program, a first-of-its-kind initiative designed to train early- to mid-career researchers to accelerate the translation of evidence into everyday care.” Full

Video: Canadian Medical Association Warns Alberta’s Use of Notwithstanding Clause Puts Politics Ahead of Evidence-Based Medicine

(11/19, Global News) “CMA president Dr. Margot Burnell joined Global News Morning expressing deep concern Alberta's move overrides medical expertise and risks eroding evidence-based health care across Canada.” View Video

Journals

Cardiovascular Outcomes of Semaglutide and Tirzepatide for Patients with Type 2 Diabetes in Clinical Practice

Nils Krüger, et al.

November 9, 2025, Nature Medicine

Nature Medicine

A Comparative Effectiveness Study of Two Narrow-Profile Staplers Used in Video-Assisted Thoracoscopic Lobectomy

I-Wen Pan, Zasim Azhar Siddiqui

November 13, 2025, Medical Devices

PubMed