CER Daily Newsfeed

Validating AI in Health Care: The Role of Real-World Evidence

(2/11, Jeanna Blitz, MD, KevinMD.com) comments “...RWE can test algorithms across populations, workflows, and datasets. Done well, it can show how technical metrics like discrimination, calibration, or drift are linked to clinical and quality outcomes such as utilization and error rates, tracking performance over time, and logging meaningful changes. RWE studies work best when they follow a pre-specified analysis plan, offering a transparent and practical way to show when an AI tool is safe, effective, and equitable in real-world care, and to reveal where it isn’t.” Full

Trump Administration Revives Effort to Launch Pilot Initiative Reworking Drug Discount Program

(2/10, Ed Silverman, STAT+) reports “...In a little-noticed posting, the Health Resources and Services Administration indicated it is pursuing a rule for a rebate model, although details were not disclosed. A previously proposed pilot program would have allowed drugmakers to offer rebates to hospitals after a medicine is dispensed, instead of providing discounts at the time of purchase.” Subscription Required

UK Moves Ahead with GP Patient Data Sharing Plan

(2/11, Phil Taylor, PharmaPhorum) reports “...‘Data from primary care is often the richest source of health information, containing real-world evidence about the multiple conditions that many people live with. We look forward to seeing the results of research that will now be possible, tackling a huge range of different diseases, ranging from arthritis and asthma, to dementia and diabetes[,’ commented Nicola Perrin, CEO of the Association of Medical Research Charities.]” Full