CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Wednesday, April 15, 2026

Articles

Pharma Gets Win in Court Appeal Over Maryland Drug Discount Law

(4/14, Nyah Phengsitthy, Bloomberg Law) reports “The US Court of Appeals for the Fourth Circuit ruled a lower court ‘erred’ when it denied the drugmakers and the Pharmaceutical Research and Manufacturers of America's motion for a preliminary injunction against Maryland's H.B. 1056. The law, currently in effect, requires manufacturers to distribute discounted drugs to an unlimited number of pharmacies that contract with health providers under the federal 340B Drug Pricing Program. The decision was driven by a recent order from the Fourth Circuit that upheld a block on West Virginia's version of the contract pharmacy law, according to the majority opinion written by Judge Julius Richardson and joined by Judge Allison Jones Rushing.” Subscription Required

 

Worrisome Bill Could Worsen Brazil’s HTA Landscape, Say Critics

(4/15, Francesca Bruce, Pink Sheet) reports “...Moves to reorganize Brazil’s health technology appraisal system would make the national health service vulnerable to pharmaceutical industry interests, warn critics.” Subscription Required

Press Releases

Folia Health Launches “BRAVE-PWS” Study to Better Understand the Real-World Experience of Prader-Willi Syndrome Caregivers

(4/15, Folia Health Press Release) “Folia Health announces the launch of Burden and Real-world Assessment of Caregiver Voice and Experiences in Prader-Willi syndrome (BRAVE-PWS), a fully remote observational study, sponsored by Soleno Therapeutics, designed to better understand the real-world experience of caregivers supporting individuals with Prader-Willi syndrome (PWS). The study will use Folia’s app-based platform to collect Home-Reported Outcomes (HROs) and longitudinal caregiver-reported data over six months, helping researchers characterize the day-to-day experience associated with PWS and identify the factors that most affect caregiver well-being and household functioning.” Full

Journals

Comparative Cardiovascular Effectiveness of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Diabetes Mellitus

Fan Bu, et al.

April 3, 2026, Journal of the American College of Cardiology

PubMed

 

Mapping the Use of Real-World Evidence Across the EU Health Technology Assessment Regulation: Methodological Considerations, Challenges, and Opportunities for Harmonization

Grammati Sarri, et al.

April 8, 2026, Journal of Market Access & Health Policy

Journal of Market Access & Health Policy

 

Comparative Effectiveness of Upadacitinib vs. Other JAK Inhibitors in Patients With Rheumatoid Arthritis in a Global Real-World Setting

Peter C Taylor, et al.

April 14, 2026, Rheumatology and Therapy

PubMed

 

First-Line Treatment of IGHV-Unmutated Chronic Lymphocytic Leukemia: A Network Meta-Analysis of Targeted and Chemoimmunotherapy Regimens

Santino Caserta, et al.

April 14, 2026, European Journal of Haematology

PubMed

 

International Reference Pricing Across Medicare and Medicaid: Evaluating CMS Models

So-Yeon Kang, PhD, MBA; Michael J. DiStefano, PhD

April 15, 2026, JAMA

JAMA