News from Thursday, October 2, 2025
Articles
What Is Meaningful Engagement in Research and Why Is It Important?
(10/2, The PCORI Blog) comments “...Engagement in PCORI-funded patient-centered CER studies can take many forms and occurs along a continuum ranging from input to consultation to collaboration and shared leadership. However, input alone, such as conducting a survey or a focus group, is not considered meaningful engagement. Instead, researchers are expected to move beyond input by tapping into other engagement approaches such as consultation, collaboration and shared leadership.” Full
A New PCORnet® Playbook Module Offers Guidance on Sharing Research Results to Improve Health Outcomes
(10/1, PCORnet Blog) comments “...A new PCORnet® Playbook module, Module 4: Sharing Your Research Results, is now available to guide you in broadly disseminating your research findings in ways that are meaningful and actionable to improve health outcomes. Module 4 describes several dissemination strategies and methods that may be used by a variety of studies, along with resources and examples to inspire you as you’re developing your own dissemination plan.” Full
Press Releases
Milliman MedInsight ACO Clients Achieve $658 Million in Savings, Outperforming National Averages in the 2024 Medicare Shared Savings Program
(10/2, Milliman MedInsight Press Release) “...‘The exceptional performance of our ACO clients in the 2024 Medicare Shared Savings Program — achieving $658 million in shared savings and outperforming national benchmarks across key measures — demonstrates the power of combining advanced analytics with deep industry expertise to drive measurable improvements in quality, efficiency, and patient outcomes,’ said Meghan Fetherston, Chief Client Officer at MedInsight. ‘Our commitment remains steadfast — to equip our clients with the insights and tools they need to thrive in value-based care.’” Full
Journals
Comparative Effectiveness of Vasopressin, Steroids, and Epinephrine-Based Regimens in Cardiac Arrest: A Network Meta-Analysis of Clinical Trials
Fatemeh Saghafi, et al.
September 23, 2025, The American Journal of Emergency Medicine
Real-World Comparative Effectiveness of Ferric Derisomaltose Versus Conventional Iron Treatment in Postpartum Hemorrhage-Related Anemia
Takuya Misugi, et al.
September 29, 2025, Cureus
Comparative Effectiveness of Direct-Acting Antiviral Treatment for Hepatitis C Virus Infection on Depressive Symptoms in Patients With Posttraumatic Stress Disorder
Brian Shiner, et al.
September 30, 2025, Clinical Therapeutics
R WE Ready for Reimbursement? A Round-Up of Developments in Real-World Evidence Relating to Health Technology Assessment: Part 21
Paul Arora and Sreeram V Ramagopalan
October 2, 2025, Journal of Comparative Effectiveness Research
Reports
The CAR T-Cell Therapy Transformation: Understanding the Technology, Current Landscape, and Future Directions
September 2025
Events
Promise of Precision Medicine and Immunotherapies for Cancer Care
October 8, 2025
12:00PM EDT