CER Daily Newsfeed

The Comparative Effectiveness Research Daily Newsfeed®, known for short as the CER Daily Newsfeed®, offers the latest news, research and related information on comparative effectiveness research, real-world data and evidence, value assessment and other important health care topics. 

News from Thursday, January 22, 2026

Articles

Comparative Effectiveness of Diabetes Medications Revealed

(1/22, Bioengineer.org) reports “...Among the key findings, the study reveals significant variations in treatment effectiveness across different medications. For instance, some agents were found to lead to more substantial improvements in glycemic control compared to others, indicating a need for personalized medicine in diabetes care. Additionally, the implications of these findings extend beyond just clinical outcomes; they also touch upon quality of life measures which are critical considerations for patients managing chronic conditions.” Full

 

SGLT2 Inhibitors Linked to Lower Risk of CKD, AKI Than GLP-1 RAs

(1/21, Pearl Steinzor, The American Journal of Managed Care) reports “...‘Notably, the differences in kidney outcomes were consistent across subgroups and most pronounced among individuals without preexisting kidney disease, which underscores a potential for primary prevention,’ wrote the researchers. ‘Importantly, the divergent outcomes of eGFR [estimated glomerular filtration rate] and albuminuria suggest that combined treatment may offer additive benefits, which should be explored in future studies.’” Full

 

Comparing COPD Treatments: FF/1 UMEC/VI vs. BUD/GLY/FORM

(1/22, Bioengineer.org) reports “...A pivotal study by Wedzicha et al. has sparked a response that delves into the comparative effectiveness of different treatment combinations for patients transitioning from dual therapy to more advanced pharmacological interventions. This discourse not only highlights the evolving landscape of COPD management but also underscores the pressing need for continued research in this domain.” Full

Press Releases

Thousands Living with Lupus Offered Hope from Twice-Yearly Infusion

(1/22, NICE Press Release) “The treatment has been approved for NHS use, offering new hope to the nearly 12,000 people in England living with lupus nephritis. Obinutuzumab (Gazyvaro), a twice-yearly infusion that, combined with daily immunosuppressant tablets, significantly outperforms the usual treatments for the disease.” Full

Journals

Comparative Effectiveness of Bone-Protective Interventions for Aromatase Inhibitors-Induced Bone Loss in Postmenopausal Women with Early Breast Cancer: A Network Meta-Analysis

Yonghui Xu, et al.

January 6, 2026, Frontiers in Oncology

PubMed

 

Comparative Effectiveness of Current Glucose-Lowering Medications in Type 2 Diabetes Mellitus: Emulation of a Modified GRADE Trial

Avik Ray MD, MS, et al.

January 21, 2026, Journal of General Internal Medicine

Springer

 

NMA: Network Meta-Analysis Based on Multivariate Meta-Analysis and Meta-Regression Models in R

Hisashi Noma, et al.

January 21, 2026, medRxiv

medRxiv

 

Response to: Letter to the Editor Regarding “Comparative Effectiveness of FF/1 UMEC/VI and BUD/GLY/FORM in Patients with COPD Stepping Up From Dual Therapy”

Jadwiga A. Wedzicha, et al.

January 22, 2026, Advances in Therapy

Springer

 

Patient-Reported Outcomes and Multiple Sclerosis Therapies

Paola Zaratin, et al.

February 2026, The Lancet Neurology

The Lancet Neurology